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We also examined whether the macrocycles could cross-bind to murine and canine Met ectodomains, in addition to the human Met ectodomain used for selection

This effect may be mediated by inhibiting Wnt-driven epithelial proliferation and dysfunction, and by correcting solute transport disorders that control the physiological balance of the Na + /Cl - (decreased fecal Na + and Cl - levels, increased serum Na + and Cl - levels), and reducing serum total protein [87,88,89]

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